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What evidence persuades us that a cancer arises from the native tissues of an individual rather than Show more What evidence persuades us that a cancer arises from the native tissues of an individual rather than invading the body from outside and thus being of foreign origin? Under certain circumstances all tumors of a class can be traced to a speci c embryonic cell layer while in other classes of tumors no such association can be made. What tumors would t into each of these two groupings? How compelling are the arguments for the monoclonal- ity of tumor cell populations and what logic and observa- tions undermine the conclusion of monoclonality? Show less
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