PCB 4023 Molecular & Cell Biology Course Paper

PCB 4023 Molecular & Cell Biology Course Paper

A Nobel Endeavor: Review of scientific discovery and innovation in cell & molecular biology 

The Nobel Prize in Physiology or Medicine 2006 Andrew Z. Fire and Craig C. Mello “for their discovery of RNA interference – gene silencing by double-stranded RNA”

Preface

Over the past 30 years significant strides have been made that vastly expanded our knowledge and understanding of biological phenomena.  Some of these scientific breakthroughs have received great accolades in recognition of their importance and impact. For this paper you will write a review of a selected Nobel prize-winning research that led to a major discovery of an important biological process/principle or scientific innovation related to topics covered by this course.

You must choose ONE scientific discovery from the list provided and your review must include the following components: 

• Introduction.  A description of the scientific discovery and the scientist(s) who conducted the research.
  • The institutions and relevant period of time where/when the work was done.
  • Citation(s) of the original publication(s) of the research.
  • Description of the current knowledge at that time.  What was known? What was unknown? Were there any other competing theories or alternative points of view?
• Experimental Methodology.  A description of ONE of the experimental methods used by the investigator(s).  Describe the results and conclusions of the experiment.
• Illustration.  Include a diagram illustrating the mechanism/process/principle identified.  The illustration must be properly cited from its original source. PCB 4023 Molecular & Cell Biology Course Paper
• Impact.  Describe the significance of the investigators’ findings and its impact on our knowledge of molecular biology.  Cite at least one example of research that was based on the original discovery.

• Your review should be 3 – 4 pages in length (min: 3, max: 4) typed, normal-spaced 12-pt font.  A bibliography in APA format is REQUIRED and is not included in your page count.  Do not add cover pages, photos or charts to your review. This is an assessment of your original writing so please review the College’s policies on academic dishonesty and plagiarism at http://www.mdc.edu/policy/student_rights_and_responsibilities.pdf.
• The grading parameters are as follows:

Paper Component	Points Awarded
Introduction	15
Experimental Methodology	10
Impact	10
Illustration	5
Bibliography	5
Presentation (spelling, grammar, creativity)	5
Total	50

PCB 4023 Molecular & Cell Biology Course Paper

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