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a) Explain the mechanisms of the radiosensitization effect of oxygen. (3
marks)
b) Define oxygen enhancement ratio (OER) and give a value for low LET
radiation.
(2
marks)
c) Describe the function of a tumour suppressor gene and the cellular
effect of loss of heterozygosity in the gene.
(3
marks)
d) Describe a “telomere” and its function. (2
marks)
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